Tohoku University Technology: Method for Producing Antimicrobial Peptides: T24-051
Low-cost production method of the antimicrobial peptide Persulcatusin for the prevention and treatment of livestock diseases.
Antibiotics used in livestock disease control tend to be avoided not only due to concerns about the emergence of drug-resistant bacteria (multidrug-resistant bacteria) similar to their use in human disease treatment, but also due to concerns about food safety from residues in eggs, raw milk, and meat. On the other hand, there is a challenge in that there are few effective preventive and treatment methods that do not use antibiotics for diseases of livestock, such as mastitis in dairy cows, which result in significant economic losses. Associate Professor Ito and others from Tohoku University Graduate School of Agriculture have developed a method to efficiently produce the antimicrobial peptide Persulcatusin (IP), known primarily for its effects on Gram-positive bacteria, using plants. This method incorporates a strategy to suppress the negative effects of the peptide by producing it as a fusion protein in the host plant, allowing the peptide to be automatically released and activated during protein extraction.
- Company：Tohoku Techno Arch Co., Ltd.
- Price：Other
